Yes you can use a question mark at the end of course. But not necessarily is a question that needs an answer, its more like a Great Greeting!
How are you, you Men of Earth
How are you? - 1st part is a question
you Men of Earth! - 2nd part more like a great greeting, for men who are being shared a great respect, for their work, or maybe their high position.
dhe/u means soil. But it would not sound good in english if we'd say: Men of soil!
This is one the the unique albanian expressions, from which u can only understand the meaning, and not be able to translate appropriate!