I think that "what's up" is more like a "hello". If so, you should change it into "ä½ å¥½å·ç ?", otherwise in Chinese it sound's like something bad happened and you are asking what happened, or that you had been a little disturbed by that mail.
U vleresua ose u publikua se fundi nga pluiepoco - 30 Prill 2008 10:00